Live news , top stories, corporate news, company news, sector news, economy news, results analysis news, ceo interviews, fund manager interview, advisor interview, market news, bazaar talk, hot stocks news, ipo news, commodities news, mutual fund news, insurance news, news wire
18 January, 2021 06:22 IST
Favipiravir drug leads to significant improvement in clinical cure in patients with mild to moderate COVID-19: Glenmark study
Source: IRIS | 23 Nov, 2020, 04.41PM
Rating: NAN / 5 stars.
Comments  |  Post Comment

 Glenmark Pharmaceuticals (Glenmark), a manufacturer of generic formulation products and API, announced that it has conducted Phase 3 clinical study on oral antiviral Favipiravir (FabiFlu) drug.

The oral antiviral medication Favipiravir, that prevents the replication phase of the virus life-cycle, leads to significant improvement in clinical cure in patients with mild to moderate COVID-19. These findings were observed in a randomized, controlled Phase 3 clinical study conducted by Glenmark Pharmaceuticals, and the results are now published online in The International Journal of Infectious Diseases (IJID).

The Phase 3 study with antiviral drug Favipiravir, brand name FabiFlu, was conducted in 150 patients as part of a randomised, open label, multicenter, Phase 3 study. Favipiravir was found to provide multiple treatment benefits, demonstrated by faster time to clinical cure, and significantly delayed the need for supportive oxygen therapy. Additionally, patients of confirmed COVID-19 with moderate symptoms were discharged from hospital earlier than those patients that did not receive Favipiravir, with the median time to clinical cure reduced by 2.5 days compared with the control group.

Favipiravir is an antiviral medication that works by inhibiting a viral enzyme called RdRP (RNA dependent RNA polymerase), thereby halting the virus's replication cycle. This helps control the multiplication of the virus and prevents its spread in the patient.

Zarir F. Udwadia. MD, FRCP, FCCP, Breach Candy Hospital, Mumbai commented "Every claim for the efficacy of a new drug in COVID-19 must be backed by evidence from a clinical trial. Glenmark has done just that with Favipiravir. Their well-designed trial in 150 patients showed Favipiravir resulted in a significantly improved time to clinical cure and rapid viral clearance. Based on this I would consider the use of this anti-viral drug in symptomatic patients with mild to moderate COVID-19. I eagerly await the results of similar trials presently being conducted in Boston and at Stanford."

Robert Crockart, Chief Commercial Officer Glenmark Pharmaceuticals said, "From the first reported case of COVID-19, our every effort was to bring a viable, safe and effective treatment option to patients in a timely manner. It is encouraging to see our trial results now published in a reputed global medical journal, which we hope will support other countries in their fight against this disease."

"The study, which was undertaken by Glenmark Pharmaceuticals, at a time when the number of cases for infections were dramatically increasing around the globe, demonstrates Glenmark's commitment to ensuring all patients have access to affordable medication, to make a positive impact on their quality of life," said Monika Tandon, Vice President & Head - Clinical Development, Global Specialty/Branded Portfolio at Glenmark.

In June 2020, Glenmark received manufacturing and marketing approval from India's drug regulator for Favipiravir (FabiFlu), making it the first oral approved medication in India for the treatment of mild to moderate COVID-19. The manufacturing and marketing approval was granted as part of an accelerated approval process, considering the emergency situation of the COVID-19 outbreak in India. The approval's restricted use entails responsible medication use where every patient must have signed informed consent before treatment initiation.

Shares of the company declined Rs 1.95, or 0.41%, to trade  at  Rs 479.50.  The total volume of shares traded  was  132,619 at  the BSE (Monday).



 Post Comment
Name Email
Comment
Security Code type    into this box
Company Update
Gravita India signs agreement with Sorin Corporation - 18-Jan-2021 13:00
Caplin Point Lab subsidiary in partnership with JAMP Pharma Group - 18-Jan-2021 12:49
Fiat Chrysler partners with Wipro for its first global digital hub in India - 15-Jan-2021 20:06
Bharti Airtel divests stake in Seynse Technologies - 15-Jan-2021 19:39
HCL Tech Q3 net profit rises 26.7%, crosses USD 10 bn revenue milestone in 2020 - 15-Jan-2021 19:13
GAIL board approves Rs 10,463.5 mn share buyback - 15-Jan-2021 18:37
Steel Strips Wheels bags export orders from Europe - 15-Jan-2021 18:11
PVR reports net loss of Rs 492.1 mn in Q3 - 15-Jan-2021 17:07
Tata Elxsi Q3 net profit rises 39.5% - 15-Jan-2021 15:37
ABB India join hands with Surat Municipal Corporation - 15-Jan-2021 14:50
NTPC arm commissions solar power project in Kerala - 15-Jan-2021 14:18
more...
Home  |   Shares  |   F&O  |   Mutual Funds  |   Loans  |   Insurance  |   News Centre
Wealth Tracker  |   Newsletters  |   Tax Corner  |   NRI Centre  |   Advertise
© All rights reserved. IRIS Business Services Limited
A Disclaimer